JMJD2D Positive Control peptide (STJ504332)

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STJ504332-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : JMJD2D Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: KDM4D
Gene ID: 55693
Uniprot ID: KDM4D_HUMAN
Post Translational Modifications Ubiquitinated via 'Lys-63'-linked ubiquitin chains. Deubiquitinated by USP14 with the help of TRIM14 leading to stabilization.
Function Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
Peptide Name Lysine-Specific Demethylase 4d
Jmjc Domain-Containing Histone Demethylation Protein 3d
Jumonji Domain-Containing Protein 2d
Histone H3-Trimethyl-L-Lysine(9 Demethylase 4d
Database Links Reactome: R-HSA-3214842
Cellular Localisation Nucleus
Alternative Peptide Names Lysine-Specific Demethylase 4d protein
Jmjc Domain-Containing Histone Demethylation Protein 3d protein
Jumonji Domain-Containing Protein 2d protein
Histone H3-Trimethyl-L-Lysine(9 Demethylase 4d protein
KDM4D protein
JHDM3D protein
JMJD2D protein

Information sourced from Uniprot.org

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