IL18RAP Blocking Peptide for STJ501437 peptide (STJ505482)

SKU:
STJ505482-250

£289.50
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: IL18RAP Blocking Peptide for STJ501437 is synthetically produced from the 500-550 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: IL18RAP
Gene ID: 8807
Uniprot ID: I18RA_HUMAN
Immunogen Region: 500-550
Specificity: This blocking peptide is recommended for use in combination with IL18RAP antibody, STJ501437
Immunogen: Synthetic peptide taken within amino acid region 500-550 on human Interleukin-18 receptor accessory protein.
Tissue Specificity Detected in adrenal gland, bone marrow, brain, fetal brain, fetal liver, heart, kidney, lung, liver, peripheral blood leukocytes, placenta, prostate, salivary gland, skeletal muscle, spinal cord, testis, thymus, thyroid, trachea and uterus. Strongly expressed in peripheral blood leukocytes and spleen and, to a lesser extent, in colon. Specifically coexpressed with IL18R1 in T-helper 1 (Th1)cells.
Post Translational Modifications N-glycosylated.
Function Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).
Peptide Name Interleukin-18 Receptor Accessory Protein
Il-18 Receptor Accessory Protein
Il-18racp
Accessory Protein-Like
Acpl
Cd218 Antigen-Like Family Member B
Cdw218b
Il-1r Accessory Protein-Like
Il-1racpl
Interleukin-1 Receptor 7
Il-1r-7
Il-1r7
Interleukin-18 Receptor Accessory Protein-Like
Interleukin-18 Receptor Beta
Il-18r-Beta
Il-18rbeta
Cd Antigen Cd218b
Database Links Reactome: R-HSA-9012546
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Peptide Names Interleukin-18 Receptor Accessory Protein protein
Il-18 Receptor Accessory Protein protein
Il-18racp protein
Accessory Protein-Like protein
Acpl protein
Cd218 Antigen-Like Family Member B protein
Cdw218b protein
Il-1r Accessory Protein-Like protein
Il-1racpl protein
Interleukin-1 Receptor 7 protein
Il-1r-7 protein
Il-1r7 protein
Interleukin-18 Receptor Accessory Protein-Like protein
Interleukin-18 Receptor Beta protein
Il-18r-Beta protein
Il-18rbeta protein
Cd Antigen Cd218b protein
IL18RAP protein
IL1R7 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance