Human ZP3 protein (Recombinant) (N-His) (STJP010884)

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STJP010884
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ZP3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ZP3
Gene ID: 7784
Uniprot ID: ZP3_HUMAN
Immunogen Region: Thr171-Gly363
Immunogen: Homo sapiens (Human)
Post Translational Modifications Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. N-glycosylated. O-glycosylated.removal of O-linked glycans may play an important role in the post-fertilization block to polyspermy.
Function Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
Protein Name Zona Pellucida Sperm-Binding Protein 3
Sperm Receptor
Zp3a/Zp3b
Zona Pellucida Glycoprotein 3
Zp-3
Zona Pellucida Protein C Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 3
Database Links Reactome: R-HSA-2534343
Cellular Localisation Processed Zona Pellucida Sperm-Binding Protein 3: Zona Pellucida
Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Zona Pellucida Sperm-Binding Protein 3 protein
Sperm Receptor protein
Zp3a/Zp3b protein
Zona Pellucida Glycoprotein 3 protein
Zp-3 protein
Zona Pellucida Protein C Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 3 protein
ZP3 protein
ZP3A protein
ZP3B protein
ZPC protein

Information sourced from Uniprot.org

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