| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.60ng/mL |
| Detection Limit: | 1.25-80ng/mL |
| Short Description: | This ZFHX1B Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | ZEB2 |
| Gene ID: | 9839 |
| Uniprot ID: | ZEB2_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Sumoylation on Lys-391 and Lys-866 is promoted by the E3 SUMO-protein ligase CBX4, and impairs interaction with CTBP1 and transcription repression activity. |
| Function | Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin. Represses expression of MEOX2. |
| Protein Name | Zinc Finger E-Box-Binding Homeobox 2 Smad-Interacting Protein 1 Smadip1 Zinc Finger Homeobox Protein 1b |
| Database Links | Reactome: R-HSA-9762293 Reactome: R-HSA-9823739 Reactome: R-HSA-9832991 |
| Cellular Localisation | Nucleus Chromosome |
| Alternative ELISA Names | Zinc Finger E-Box-Binding Homeobox 2 ELISA kit Smad-Interacting Protein 1 ELISA kit Smadip1 ELISA kit Zinc Finger Homeobox Protein 1b ELISA kit ZEB2 ELISA kit KIAA0569 ELISA kit SIP1 ELISA kit ZFHX1B ELISA kit ZFX1B ELISA kit HRIHFB2411 ELISA kit |
| output |
Information sourced from Uniprot.org
