| Function | Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-ACACATCTGGTAC-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus. |
| Protein Name | Zinc Finger And Btb Domain-Containing Protein 1858 Kda Repressor ProteinTranscriptional Repressor Rp58Translin-Associated Zinc Finger Protein 1Taz-1Zinc Finger Protein 238Zinc Finger Protein C2h2-171 |
| Cellular Localisation | NucleusAssociates With Condensed Chromatin |
| Alternative Protein Names | Zinc Finger And Btb Domain-Containing Protein 18 protein58 Kda Repressor Protein proteinTranscriptional Repressor Rp58 proteinTranslin-Associated Zinc Finger Protein 1 proteinTaz-1 proteinZinc Finger Protein 238 proteinZinc Finger Protein C2h2-171 proteinZBTB18 proteinRP58 proteinTAZ1 proteinZNF238 protein |
Information sourced from Uniprot.org
