Human ZBTB18 protein (Recombinant) (N-His) (STJP008291)

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STJP008291
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Short Description :Recombinant-Human ZBTB18-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:ZBTB18
Gene ID:10472
Uniprot ID:ZBT18_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met1-Thr128
Function Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-ACACATCTGGTAC-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus.
Protein Name Zinc Finger And Btb Domain-Containing Protein 18
58 Kda Repressor Protein
Transcriptional Repressor Rp58
Translin-Associated Zinc Finger Protein 1
Taz-1
Zinc Finger Protein 238
Zinc Finger Protein C2h2-171
Database Links
Cellular Localisation Nucleus
Associates With Condensed Chromatin
Alternative Protein Names Zinc Finger And Btb Domain-Containing Protein 18 protein
58 Kda Repressor Protein protein
Transcriptional Repressor Rp58 protein
Translin-Associated Zinc Finger Protein 1 protein
Taz-1 protein
Zinc Finger Protein 238 protein
Zinc Finger Protein C2h2-171 protein
ZBTB18 protein
RP58 protein
TAZ1 protein
ZNF238 protein

Information sourced from Uniprot.org