| Host: | E.coli |
| Applications: | SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human XCL1/Lymphotactin-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 30% Glycerol 2mM DTT, 0.2 M NaCl. |
| Concentration: | 0.25 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Gene Symbol: | XCL1 |
| Gene ID: | 6375 |
| Uniprot ID: | XCL1_HUMAN |
| Immunogen Region: | 22-114aa |
| Accession Number: | NP_002986 |
| Immunogen: | Human |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MVGSEVSDKR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG |
| Tissue Specificity | Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine. |
| Function | Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment. |
| Protein Name | LymphotactinAtacC Motif Chemokine 1Cytokine Scm-1LymphotaxinScm-1-AlphaSmall-Inducible Cytokine C1Xc Chemokine Ligand 1 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-416476 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Lymphotactin proteinAtac proteinC Motif Chemokine 1 proteinCytokine Scm-1 proteinLymphotaxin proteinScm-1-Alpha proteinSmall-Inducible Cytokine C1 proteinXc Chemokine Ligand 1 proteinXCL1 proteinLTN proteinSCYC1 protein |
Information sourced from Uniprot.org
