Human WNT10B protein (Recombinant) (N-His) (STJP003170)

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STJP003170
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human WNT10B-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: WNT10B
Gene ID: 7480
Uniprot ID: WN10B_HUMAN
Immunogen Region: Glu30-Pro322
Immunogen: Homo sapiens (Human)
Post Translational Modifications Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Function Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade. Specifically activates canonical Wnt/beta-catenin signaling and thus triggers beta-catenin/LEF/TCF-mediated transcriptional programs. Involved in signaling networks controlling stemness, pluripotency and cell fate decisions. Acts in the immune system, mammary gland, adipose tissue, bone and skin.
Protein Name Protein Wnt-10b
Protein Wnt-12
Database Links Reactome: R-HSA-3238698
Reactome: R-HSA-373080
Reactome: R-HSA-381340
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Protein Names Protein Wnt-10b protein
Protein Wnt-12 protein
WNT10B protein
WNT12 protein

Information sourced from Uniprot.org

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