Human WLS protein (Recombinant) (N-His) (STJP008187)

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STJP008187
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human WLS-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: WLS
Gene ID: 79971
Uniprot ID: WLS_HUMAN
Immunogen Region: Thr40-Asn227
Immunogen: Homo sapiens (Human)
Function Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development.
Protein Name Protein Wntless Homolog
Integral Membrane Protein Gpr177
Protein Evenness Interrupted Homolog
Evi
Putative Nf-Kappa-B-Activating Protein 373
Database Links Reactome: R-HSA-3238698
Cellular Localisation Golgi Apparatus Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle Membrane
Cell Membrane
Endoplasmic Reticulum Membrane
Early Endosome Membrane
Co-Localizes With The Adaptin Ap2a2 At Distinct Punctae
Alternative Protein Names Protein Wntless Homolog protein
Integral Membrane Protein Gpr177 protein
Protein Evenness Interrupted Homolog protein
Evi protein
Putative Nf-Kappa-B-Activating Protein 373 protein
WLS protein
C1orf139 protein
GPR177 protein
UNQ85 protein
PRO18667 protein

Information sourced from Uniprot.org