Function | Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development. |
Protein Name | Protein Wntless HomologIntegral Membrane Protein Gpr177Protein Evenness Interrupted HomologEviPutative Nf-Kappa-B-Activating Protein 373 |
Database Links | Reactome: R-HSA-3238698 |
Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembraneCell MembraneEndoplasmic Reticulum MembraneEarly Endosome MembraneCo-Localizes With The Adaptin Ap2a2 At Distinct Punctae |
Alternative Protein Names | Protein Wntless Homolog proteinIntegral Membrane Protein Gpr177 proteinProtein Evenness Interrupted Homolog proteinEvi proteinPutative Nf-Kappa-B-Activating Protein 373 proteinWLS proteinC1orf139 proteinGPR177 proteinUNQ85 proteinPRO18667 protein |
Information sourced from Uniprot.org