Human WIF-1 (Q166K) protein (Recombinant) (C-His) (STJP000963)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human WIF-1 (Q166K) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly29-Trp379 (Gln166Lys) ) of human WIF-1 (Accession #NP_009122.2) fused with a 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human WIF-1 (Q166K)-C-His protein was developed in hek293 cells using the region Gly29-Trp379Gln166Lys. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of 20mM HAc-NaAc, 150mM NaCl, 0.5% CHAPS, pH 6.0. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | WIF1 |
| Gene ID | 11197 |
| Uniprot ID | WIF1_HUMAN |
| Immunogen | Recombinant Human WIF-1 (Q166K) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly29-Trp379 (Gln166Lys) ) of human WIF-1 (Accession #NP_009122.2) fused with a 6×His tag at the C-terminus. |
| Immunogen Region | Gly29-Trp379Gln166Lys |
| Immunogen Sequence | GPPQEESLYLWIDAHQARVL IGFEEDILIVSEGKMAPFTH DFRKAQQRMPAIPVNIHSMN FTWQAAGQAEYFYEFLSLRS LDKGIMADPTVNVPLLGTVP HKASVVQVGFPCLGKQDGVA AFEVDVIVMNSEGNTILKTP QNAIFFKTCQQAECPGGCRN GGFCNERRICECPDGFHGPH CEKALCTPRCMNGGLCVTPG FCICPPGFYGVNCDKANCST TCFNGGTCFYPGKCICPPG |
Additional Info
| Function | Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. |
| Protein Name | Wnt Inhibitory Factor 1Wif-1 |
| Database Links | Reactome: R-HSA-201681Reactome: R-HSA-3772470 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Wnt Inhibitory Factor 1 proteinWif-1 proteinWIF1 proteinUNQ191 proteinPRO217 protein |
Information sourced from Uniprot.org