Human WFS1 (Wolfram Syndrome Protein 1) Sandwich ELISA Kit Kit (STJE0013084)

Human WFS1 (Wolfram Syndrome Protein 1) Sandwich ELISA Kit Kit (STJE0013084)

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STJE0013084
£501.50 - £688.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.103ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This WFS1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: WFS1
Gene ID: 7466
Uniprot ID: WFS1_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Highly expressed in heart followed by brain, placenta, lung and pancreas. Weakly expressed in liver, kidney and skeletal muscle. Also expressed in islet and beta-cell insulinoma cell line.
Post Translational Modifications
Function Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store. Negatively regulates the ER stress response and positively regulates the stability of V-ATPase subunits ATP6V1A and ATP1B1 by preventing their degradation through an unknown proteasome-independent mechanism.
Protein Name Wolframin
Database Links Reactome: R-HSA-381038
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle
Secretory Vesicle
Co-Localizes With Atp6v1a In The Secretory Granules In Neuroblastoma Cell Lines
Alternative ELISA Names Wolframin ELISA kit
WFS1 ELISA kit
output

Information sourced from Uniprot.org

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