Human WBP2 protein (Recombinant) (N-His) (STJP007841)

SKU:
STJP007841
£328.50 - £1,437.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human WBP2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: WBP2
Gene ID: 23558
Uniprot ID: WBP2_HUMAN
Immunogen Region: Met1-Gly136
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated in repsonse to EGF as well as estrogen and progesterone hormones. Tyr-192 and Tyr-231 are phosphorylated by YES and SRC inducing nuclear translocation.
Function Acts as a transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation. In presence of estrogen, binds to ESR1-responsive promoters. Synergizes with YAP1 to enhance PGR activity. Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR.
Protein Name Ww Domain-Binding Protein 2
Wbp-2
Cellular Localisation Cytoplasm
Nucleus
Translocates From Cytoplasm To Nucleus When Phosphorylated
Alternative Protein Names Ww Domain-Binding Protein 2 protein
Wbp-2 protein
WBP2 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E. coli
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E. coli
STJP007878 Human GPAT3 protein (Recombinant) (N-His) (STJP007878) E. coli
STJP007867 Human NAP1L4 protein (Recombinant) (N-His) (STJP007867) E. coli
STJP007854 Human EGLN1 protein (Recombinant) (N-His) (STJP007854) E. coli

Related Products

!