Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human WAIF1/5T4/TPBG-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Gene Symbol: |
TPBG |
Gene ID: |
7162 |
Uniprot ID: |
TPBG_HUMAN |
Immunogen: |
Recombinant Human WAIF1/5T4/TPBG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser32-Ser355) of human TPBG/5T4 (Accession #NP_006661.1) fused with a 6×His tag at the C-terminus. |
Post Translational Modifications | Highly glycosylated. |
Function | May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. |
Protein Name | Trophoblast Glycoprotein5t4 Oncofetal Antigen5t4 Oncofetal Trophoblast Glycoprotein5t4 Oncotrophoblast GlycoproteinM6p1Wnt-Activated Inhibitory Factor 1Waif1 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Trophoblast Glycoprotein5t4 Oncofetal Antigen protein5t4 Oncofetal Trophoblast Glycoprotein5t4 Oncotrophoblast GlycoproteinM6p1 proteinWnt-Activated Inhibitory Factor 1 proteinWaif1 proteinTPBG protein5T4 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance