Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human WAIF1/5T4/TPBG-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Gene Symbol: | TPBG |
Gene ID: | 7162 |
Uniprot ID: | TPBG_HUMAN |
Immunogen: | Recombinant Human WAIF1/5T4/TPBG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser32-Ser355) of human TPBG/5T4 (Accession #NP_006661.1) fused with a 6×His tag at the C-terminus. |
Post Translational Modifications | Highly glycosylated. |
Function | May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. |
Protein Name | Trophoblast Glycoprotein 5t4 Oncofetal Antigen 5t4 Oncofetal Trophoblast Glycoprotein 5t4 Oncotrophoblast Glycoprotein M6p1 Wnt-Activated Inhibitory Factor 1 Waif1 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | Trophoblast Glycoprotein 5t4 Oncofetal Antigen protein 5t4 Oncofetal Trophoblast Glycoprotein 5t4 Oncotrophoblast Glycoprotein M6p1 protein Wnt-Activated Inhibitory Factor 1 protein Waif1 protein TPBG protein 5T4 protein |
Information sourced from Uniprot.org