Human WAIF1/5T4/TPBG protein (Recombinant) (C-His&Avi) {Biotin} (STJP020246)
SPECIFICATIONS
HostHEK293 cells
ConjugationBiotin
ImmunogenBiotinylated Recombinant Human WAIF1/5T4/TPBG Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ser32-Ser355) of Human TPBG fused with a His and Avi tag at the C-terminal.
General Information
| Short Description | Recombinant-Human WAIF1/5T4/TPBG-C-His&Avi protein was developed in hek293 cells using the region Ser32-Ser355. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | TPBG |
| Gene ID | 7162 |
| Uniprot ID | TPBG_HUMAN |
| Immunogen | Biotinylated Recombinant Human WAIF1/5T4/TPBG Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ser32-Ser355) of Human TPBG fused with a His and Avi tag at the C-terminal. |
| Immunogen Region | Ser32-Ser355 |
Additional Info
| Tissue Specificity | Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma. |
| Post Translational Modifications | Highly glycosylated. |
| Function | May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. |
| Protein Name | Trophoblast Glycoprotein5t4 Oncofetal Antigen5t4 Oncofetal Trophoblast Glycoprotein5t4 Oncotrophoblast GlycoproteinM6p1Wnt-Activated Inhibitory Factor 1Waif1 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Trophoblast Glycoprotein5t4 Oncofetal Antigen protein5t4 Oncofetal Trophoblast Glycoprotein5t4 Oncotrophoblast GlycoproteinM6p1 proteinWnt-Activated Inhibitory Factor 1 proteinWaif1 proteinTPBG protein5T4 protein |
Information sourced from Uniprot.org