Human WAIF1/5T4/TPBG protein (Recombinant) (C-His&Avi) {Biotin} (STJP020246)

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STJP020246
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Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Biotin
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 1 EU/Mu g of the protein by LAL method.
Gene Symbol: TPBG
Gene ID: 7162
Uniprot ID: TPBG_HUMAN
Immunogen Region: Ser32-Ser355
Immunogen: Biotinylated Recombinant Human WAIF1/5T4/TPBG Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ser32-Ser355) of Human TPBG fused with a His and Avi tag at the C-terminal.
Tissue Specificity Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
Post Translational Modifications Highly glycosylated.
Function May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
Protein Name Trophoblast Glycoprotein
5t4 Oncofetal Antigen
5t4 Oncofetal Trophoblast Glycoprotein
5t4 Oncotrophoblast Glycoprotein
M6p1
Wnt-Activated Inhibitory Factor 1
Waif1
Database Links
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Trophoblast Glycoprotein
5t4 Oncofetal Antigen protein
5t4 Oncofetal Trophoblast Glycoprotein
5t4 Oncotrophoblast Glycoprotein
M6p1 protein
Wnt-Activated Inhibitory Factor 1 protein
Waif1 protein
TPBG protein
5T4 protein

Information sourced from Uniprot.org

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