Human Vitamin D Binding protein (Vitamin D Binding protein) Antibody Pair (STJAP00927)

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STJAP00927-2
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Host: Rabbit/Rabbit
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : This Vitamin D Binding protein antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the.
Clonality : Monoclonal/Monoclonal
Clone ID : R05-1X-3/R09-6R-7
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.2
Purification: Affinity Purification
Dilution Range: Determined by end user
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: GC
Gene ID: 2638
Uniprot ID: VTDB_HUMAN
Immunogen: Recombinant protein
Tissue Specificity Expressed in the liver. Found in plasma, ascites, cerebrospinal fluid and urine.
Post Translational Modifications Allele GC*1S is O-glycosylated at Thr-436. The trisaccharide sugar moiety can be modified by the successive removal of neuraminic acid and galactose leaving an O-mceeN-acetyl-galactosamine. This conversion is thought to produce a macrophage-activating factor (Gc-MAF). Only a minor proportion of plasma GC is O-glycosylated. The potential N-glycosylation site predicted at Asn-288 is thought to be nonglycosylated.
Function Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
Protein Name Vitamin D-Binding Protein
Dbp
Vdb
Gc Protein-Derived Macrophage Activating Factor
Gc-Maf
Gcmaf
Gc-Globulin
Group-Specific Component
Gc
Vitamin D-Binding Protein-Macrophage Activating Factor
Dbp-Maf
Database Links Reactome: R-HSA-196791
Cellular Localisation Secreted
Alternative Antibody Pair Names Vitamin D-Binding Protein antibody pair
Dbp antibody pair
Vdb antibody pair
Gc Protein-Derived Macrophage Activating Factor antibody pair
Gc-Maf antibody pair
Gcmaf antibody pair
Gc-Globulin antibody pair
Group-Specific Component antibody pair
Gc antibody pair
Vitamin D-Binding Protein-Macrophage Activating Factor antibody pair
Dbp-Maf antibody pair
GC antibody pair

Information sourced from Uniprot.org

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