Human VIPR1 (Vasoactive Intestinal Peptide Receptor 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0019439)
SPECIFICATIONS
General Information
| Short Description | This VIPR1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.045ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | VIPR1 |
| Gene ID | 7433 |
| Uniprot ID | VIPR1_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T-cell lines Peer, MOLT-4, HSB and YT. |
| Post Translational Modifications | |
| Function | G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of ligand affinity VIP = PACAP27 > PACAP38. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. |
| Protein Name | Vasoactive Intestinal Polypeptide Receptor 1Vip-R-1Pituitary Adenylate Cyclase-Activating Polypeptide Type Ii ReceptorPacap Type Ii ReceptorPacap-R-2Pacap-R2Vpac1 ReceptorVpac1r |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Vasoactive Intestinal Polypeptide Receptor 1 ELISA kitVip-R-1 ELISA kitPituitary Adenylate Cyclase-Activating Polypeptide Type Ii Receptor ELISA kitPacap Type Ii Receptor ELISA kitPacap-R-2 ELISA kitPacap-R2 ELISA kitVpac1 Receptor ELISA kitVpac1r ELISA kitVIPR1 ELISA kit |
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Information sourced from Uniprot.org