| Host: | Goat/Goat |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | This VCAN antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Conjugation: | Unconjugated/Biotin |
| Concentration: | 0.5 mg/mL/0.5-4ug/mL |
| Dilution Range: | 1:1000-1:10000 |
| Storage Instruction: | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Detection: | Colorimetric method;ELISA;Sandwich |
| Gene Symbol: | VCAN |
| Gene ID: | 1462 |
| Uniprot ID: | CSPG2_HUMAN |
| Sample Type: | Serum, plasma and other biological fluids |
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. Proteolytically cleaved by ADAMTS5 and ADAMTS15 in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration. |
| Function | May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid. |
| Protein Name | Versican Core ProteinChondroitin Sulfate Proteoglycan Core Protein 2Chondroitin Sulfate Proteoglycan 2Glial Hyaluronate-Binding ProteinGhapLarge Fibroblast ProteoglycanPg-M |
| Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022870Reactome: R-HSA-2022923Reactome: R-HSA-2024101Reactome: R-HSA-3000178Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3595172Reactome: R-HSA-3595174Reactome: R-HSA-3595177Reactome: R-HSA-381426Reactome: R-HSA-4420332Reactome: R-HSA-8957275 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixCell ProjectionCiliumPhotoreceptor Outer SegmentInterphotoreceptor Matrix |
| Alternative Antibody Pair Names | Versican Core Protein antibody pairChondroitin Sulfate Proteoglycan Core Protein 2 antibody pairChondroitin Sulfate Proteoglycan 2 antibody pairGlial Hyaluronate-Binding Protein antibody pairGhap antibody pairLarge Fibroblast Proteoglycan antibody pairPg-M antibody pairVCAN antibody pairCSPG2 antibody pair |
Information sourced from Uniprot.org
