| Short Description : | Recombinant-Active-Human VASN-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. When recombinant human TGF‑ beta 1 is used at 2 µg/mL (100 µL/well) , recombinant human VASN binds with an ED50 of 0.6-3.6 Mu g/mL. |
| Gene Symbol: | VASN |
| Gene ID: | 114990 |
| Uniprot ID: | VASN_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Cys24-Asn573 |
| Post Translational Modifications | N-glycosylated. N-glycan heterogeneity at Asn-117: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major), Hex6HexNAc5 (minor) and dHex1Hex6HexNAc5 (minor). |
| Function | May act as an inhibitor of TGF-beta signaling. |
| Protein Name | VasorinProtein Slit-Like 2 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecreted |
| Alternative Protein Names | Vasorin proteinProtein Slit-Like 2 proteinVASN proteinSLITL2 proteinUNQ314 proteinPRO357 proteinPRO1282 protein |
Information sourced from Uniprot.org
