Human VAChT (Vesicular Acetylcholine Transporter) Sandwich ELISA Kit Ready-To-Use Kit (STJE0019352)

Human VAChT (Vesicular Acetylcholine Transporter) Sandwich ELISA Kit Ready-To-Use Kit (STJE0019352)

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STJE0019352
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.117ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This VAChT Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: SLC18A3
Gene ID: 6572
Uniprot ID: VACHT_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Peripheral and central cholinergic nervous systems.
Post Translational Modifications
Function Electrogenic antiporter that exchanges one cholinergic neurotransmitter, acetylcholine or choline, with two intravesicular protons across the membrane of synaptic vesicles. Uses the electrochemical proton gradient established by the V-type proton-pump ATPase to store neurotransmitters inside the vesicles prior to their release via exocytosis. Determines cholinergic vesicular quantal size at presynaptic nerve terminals in developing neuro-muscular junctions with an impact on motor neuron differentiation and innervation pattern. Part of forebrain cholinergic system, regulates hippocampal synapse transmissions that underlie spatial memory formation. Can transport serotonin.
Protein Name Vesicular Acetylcholine Transporter
Vacht
Solute Carrier Family 18 Member 3
Database Links Reactome: R-HSA-264642
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Vesicular Acetylcholine Transporter ELISA kit
Vacht ELISA kit
Solute Carrier Family 18 Member 3 ELISA kit
SLC18A3 ELISA kit
VACHT ELISA kit
output

Information sourced from Uniprot.org

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