Human UROS protein (Recombinant) (His-Tag) (STJP017201)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human UROS-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Mgu |
| Gene ID | 7390 |
| Uniprot ID | HEM4_HUMAN |
| Accession Number | NP_000366 |
| Immunogen | Human |
| Immunogen Region | 1-265aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme). |
| Protein Name | Uroporphyrinogen-Iii SynthaseUroiiisUrosHydroxymethylbilane Hydrolyase CyclizingUroporphyrinogen-Iii Cosynthase |
| Database Links | Reactome: R-HSA-189451 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Protein Names | Uroporphyrinogen-Iii Synthase proteinUroiiis proteinUros proteinHydroxymethylbilane Hydrolyase Cyclizing proteinUroporphyrinogen-Iii Cosynthase proteinMgu proteinUROS protein |
Information sourced from Uniprot.org