Human UROS protein (Recombinant) (C-His) (STJP014405)

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STJP014405-100
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Short Description :Recombinant-Human UROS-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications.
Applications:ELISA/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Formulation:Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 100mM NaCl, 10% Glycerol, pH 8.0.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:Mgu
Gene ID:7390
Uniprot ID:HEM4_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met1-Cys265
Function Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).
Protein Name Uroporphyrinogen-Iii Synthase
Uroiiis
Uros
Hydroxymethylbilane Hydrolyase Cyclizing
Uroporphyrinogen-Iii Cosynthase
Database Links Reactome: R-HSA-189451
Cellular Localisation Cytoplasm
Cytosol
Alternative Protein Names Uroporphyrinogen-Iii Synthase protein
Uroiiis protein
Uros protein
Hydroxymethylbilane Hydrolyase Cyclizing protein
Uroporphyrinogen-Iii Cosynthase protein
Mgu protein
UROS protein

Information sourced from Uniprot.org