Human uPA Receptor/U-PAR (uPA Receptor/U-PAR) Antibody Pair (STJAP00924)

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STJAP00924-2
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Short Description :This uPA Receptor/U-PAR antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the.
Applications:ELISA
Host:Rabbit/Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal/Monoclonal
Clone ID :R06-9G-1/R03-6P-1
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Purification
Dilution Range:Determined by end user
Formulation:0.01M PBS, pH 7.2
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:PLAUR
Gene ID:5329
Uniprot ID:UPAR_HUMAN
Immunogen:Recombinant protein
Tissue Specificity Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
Function Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Protein Name Urokinase Plasminogen Activator Surface Receptor
U-Par
Upar
Monocyte Activation Antigen Mo3
Cd Antigen Cd87
Database Links Reactome: R-HSA-162791
Reactome: R-HSA-6798695
Reactome: R-HSA-75205
Cellular Localisation Cell Membrane
Cell Projection
Invadopodium Membrane
Colocalized With Fap (Seprase) Preferentially At The Cell Surface Of Invadopodia Membrane In A Cytoskeleton-
Integrin- And Vitronectin-Dependent Manner
Isoform 1: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform 2: Secreted
Alternative Antibody Pair Names Urokinase Plasminogen Activator Surface Receptor antibody pair
U-Par antibody pair
Upar antibody pair
Monocyte Activation Antigen Mo3 antibody pair
Cd Antigen Cd87 antibody pair
PLAUR antibody pair
MO3 antibody pair
UPAR antibody pair

Information sourced from Uniprot.org

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