| Short Description : | Recombinant-Human UDP-glucose dehydrogenase/UGDH-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Enzyme Activity |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 1mM DTT, 0.1M NaCl, and 1mM EDTA |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Specific activity is > 2500pmol/min/ug, and is defined as the amount of enzyme that convert 1.0pmole of UDP-glucose to UDP-glucuronate per minute at pH 8.7 at 37C. |
| Gene Symbol: | UGDH |
| Gene ID: | 7358 |
| Uniprot ID: | UGDH_HUMAN |
| Accession Number: | NP_003350.1 |
| Immunogen: | Human |
| Immunogen Region: | 1-494aa |
| Immunogen Sequence: |
| Tissue Specificity | Detected in heart, placenta, liver, pancreas, spleen, thymus, prostate, ovary, small intestine and colon. Widely expressed. |
| Function | Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans. Required for proper brain and neuronal development. |
| Protein Name | Udp-Glucose 6-DehydrogenaseUdp-Glc DehydrogenaseUdp-GlcdhUdpgdh |
| Database Links | Reactome: R-HSA-173599 |
| Cellular Localisation | |
| Alternative Protein Names | Udp-Glucose 6-Dehydrogenase proteinUdp-Glc Dehydrogenase proteinUdp-Glcdh proteinUdpgdh proteinUGDH protein |
Information sourced from Uniprot.org
