Human UDP-galactose-4-epimerase/GALE protein (Recombinant) (His-Tag) (STJP016754)

SKU:
STJP016754
$173.19 - $896.31
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Short Description :Recombinant-Human UDP-galactose-4-epimerase/GALE-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 5mM DTT, 0.1M NaCl, and 1mM EDTA
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:GALE
Gene ID:2582
Uniprot ID:GALE_HUMAN
Accession Number:NP_000394.2
Immunogen:Human
Immunogen Region:1-348aa
Immunogen Sequence: MAEKVLVTGG AGYIGSHTVL ELLEAGYLPV VIDNFHNAFR GGGSLPESLR RVQELTGRSV EFEEMDILDQ GALQRLFKKY SFMAVIHFAG LKAVGESVQK PLDYYRVNLT GTIQLLEIMK AHGVKNLVFS SSATVYGNPQ YLPLDEAHPT GGCTNPYGKS KFFIEEMIRD LCQADKTWNA VLLRYFNPTG AHASGCIGED PQGIPN
Function Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
Protein Name Udp-Glucose 4-Epimerase
Galactowaldenase
Udp-N-Acetylgalactosamine 4-Epimerase
Udp-Galnac 4-Epimerase
Udp-N-Acetylglucosamine 4-Epimerase
Udp-Glcnac 4-Epimerase
Udp-Galactose 4-Epimerase
Database Links Reactome: R-HSA-5609977
Reactome: R-HSA-70370
Cellular Localisation
Alternative Protein Names Udp-Glucose 4-Epimerase protein
Galactowaldenase protein
Udp-N-Acetylgalactosamine 4-Epimerase protein
Udp-Galnac 4-Epimerase protein
Udp-N-Acetylglucosamine 4-Epimerase protein
Udp-Glcnac 4-Epimerase protein
Udp-Galactose 4-Epimerase protein
GALE protein

Information sourced from Uniprot.org