Anti-UDP-galactose-4-epimerase/GALE antibody (1-348aa) [AT6G10] (STJA0041778)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenRecombinant human GALE (1-348aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-UDP-galactose-4-epimerase/GALE (1-348aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT6G10 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GALE |
| Gene ID | 2582 |
| Uniprot ID | GALE_HUMAN |
| Accession Number | NP_000394 |
| Immunogen | Recombinant human GALE (1-348aa) purified from E. coli |
| Immunogen Region | 1-348aa |
Additional Info
| Function | Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids. |
| Protein Name | Udp-Glucose 4-EpimeraseGalactowaldenaseUdp-N-Acetylgalactosamine 4-EpimeraseUdp-Galnac 4-EpimeraseUdp-N-Acetylglucosamine 4-EpimeraseUdp-Glcnac 4-EpimeraseUdp-Galactose 4-Epimerase |
| Database Links | Reactome: R-HSA-5609977Reactome: R-HSA-70370 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Udp-Glucose 4-Epimerase antibodyAnti-Galactowaldenase antibodyAnti-Udp-N-Acetylgalactosamine 4-Epimerase antibodyAnti-Udp-Galnac 4-Epimerase antibodyAnti-Udp-N-Acetylglucosamine 4-Epimerase antibodyAnti-Udp-Glcnac 4-Epimerase antibodyAnti-Udp-Galactose 4-Epimerase antibodyAnti-GALE antibody |
Information sourced from Uniprot.org