| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human UBTF-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications. |
| Formulation: | 0.01M PBS, pH 7.4. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | UBTF |
| Gene ID: | 7343 |
| Uniprot ID: | UBF1_HUMAN |
| Immunogen Region: | Lys486-Arg549 |
| Immunogen: | Homo sapiens (Human) |
| Function | Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I (Pol I) through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element and can activate Pol I promoter escape. |
| Protein Name | Nucleolar Transcription Factor 1Autoantigen Nor-90Upstream-Binding Factor 1Ubf-1 |
| Database Links | Reactome: R-HSA-427413Reactome: R-HSA-73728Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73863 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Protein Names | Nucleolar Transcription Factor 1 proteinAutoantigen Nor-90 proteinUpstream-Binding Factor 1 proteinUbf-1 proteinUBTF proteinUBF proteinUBF1 protein |
Information sourced from Uniprot.org