| Host: | E.coli |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human UBAP1-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, 1mM DTT, pH 7.4. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | UBAP1 |
| Gene ID: | 51271 |
| Uniprot ID: | UBAP1_HUMAN |
| Immunogen Region: | Met1-Ser502 |
| Immunogen: | Homo sapiens (Human) |
| Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2. |
| Protein Name | Ubiquitin-Associated Protein 1Ubap-1Nasopharyngeal Carcinoma-Associated Gene 20 Protein |
| Database Links | Reactome: R-HSA-162588Reactome: R-HSA-174490Reactome: R-HSA-917729Reactome: R-HSA-9610379Reactome: R-HSA-9615710 |
| Cellular Localisation | CytoplasmCytosolEndosomePredominantly CytosolicRecruited To Endosomes As Part Of The Escrt-I Complex |
| Alternative Protein Names | Ubiquitin-Associated Protein 1 proteinUbap-1 proteinNasopharyngeal Carcinoma-Associated Gene 20 Protein proteinUBAP1 proteinNAG20 protein |
Information sourced from Uniprot.org