Human TSSC4 protein (Recombinant) (His-Tag) (STJP017493)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human TSSC4-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% Glycerol, 200mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TSSC4 |
| Gene ID | 10078 |
| Uniprot ID | TSSC4_HUMAN |
| Accession Number | AAH06091 |
| Immunogen | Human |
| Immunogen Region | 1-329aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in fetal brain, lung, liver and kidney. Widely expressed in adult tissues. |
| Function | Protein associated with the U5 snRNP, during its maturation and its post-splicing recycling and which is required for spliceosomal tri-snRNP complex assembly in the nucleus. Has a molecular sequestering activity and transiently hinders SNRNP200 binding sites for constitutive splicing factors that intervene later during the assembly of the spliceosome and splicing. Together with its molecular sequestering activity, may also function as a molecular adapter and placeholder, coordinating the assembly of the U5 snRNP and its association with the U4/U6 di-snRNP. |
| Protein Name | U5 Small Nuclear Ribonucleoprotein Tssc4Tumor-Suppressing Stf Cdna 4 ProteinTumor-Suppressing Subchromosomal Transferable Fragment Candidate Gene 4 Protein |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmShuttles Between The Cytoplasm And The NucleusAssociated With The U5 Snrnp |
| Alternative Protein Names | U5 Small Nuclear Ribonucleoprotein Tssc4 proteinTumor-Suppressing Stf Cdna 4 Protein proteinTumor-Suppressing Subchromosomal Transferable Fragment Candidate Gene 4 Protein proteinTSSC4 protein |
Information sourced from Uniprot.org