Human TSPYL2 protein (Recombinant) (N-His) (STJP010991)

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STJP010991
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TSPYL2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TSPYL2
Gene ID: 64061
Uniprot ID: TSYL2_HUMAN
Immunogen Region: Pro263-Arg418
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation.
Function Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
Protein Name Testis-Specific Y-Encoded-Like Protein 2
Tspy-Like Protein 2
Cell Division Autoantigen 1
Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4
Ctcl-Associated Antigen Se20-4
Differentially-Expressed Nucleolar Tgf-Beta1 Target Protein
Nuclear Protein Of 79 Kda
Np79
Database Links Reactome: R-HSA-381038
Cellular Localisation Nucleus
Cytoplasm
Enriched In Transcriptionally Active Regions Of Chromatin In Neurons
Alternative Protein Names Testis-Specific Y-Encoded-Like Protein 2 protein
Tspy-Like Protein 2 protein
Cell Division Autoantigen 1 protein
Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4 protein
Ctcl-Associated Antigen Se20-4 protein
Differentially-Expressed Nucleolar Tgf-Beta1 Target Protein protein
Nuclear Protein Of 79 Kda protein
Np79 protein
TSPYL2 protein
CDA1 protein
DENTT protein
TSPX protein
HRIHFB2216 protein

Information sourced from Uniprot.org

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