Human TSLP (R127A, R130A) protein (Recombinant) (C-His) (STJP020069)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human TSLP (R127A, R130A) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Tyr29-Gln159 (Arg127Ala, Arg130Ala) ) of human TSLP (Accession #NP_149024.1) fused with a 6×His tag at the C-t
General Information
| Short Description | Recombinant-Human TSLP (R127A, R130A)-C-His protein was developed in hek293 cells using the region Tyr29-Gln159. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | TSLP |
| Gene ID | 85480 |
| Uniprot ID | TSLP_HUMAN |
| Immunogen | Recombinant Human TSLP (R127A, R130A) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Tyr29-Gln159 (Arg127Ala, Arg130Ala) ) of human TSLP (Accession #NP_149024.1) fused with a 6×His tag at the C-t |
| Immunogen Region | Tyr29-Gln159 |
| Immunogen Sequence | YDFTNCDFEKIKAAYLSTIS KDLITYMSGTKSTEFNNTVS CSNRPHCLTEIQSLTFNPTA GCASLAKEMFAMKTKAALAI WCPGYSETQINATQAMKKAR KAKVTTNKCLEQVSQLQGLW RRFNRPLLKQQ |
Additional Info
| Function | Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin. |
| Protein Name | Thymic Stromal Lymphopoietin |
| Database Links | Reactome: R-HSA-1266695 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Thymic Stromal Lymphopoietin proteinTSLP protein |
Information sourced from Uniprot.org