| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | TSLP |
| Gene ID: | 85480 |
| Uniprot ID: | TSLP_HUMAN |
| Immunogen: | Recombinant Human TSLP (R127A, R130A) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Tyr29-Gln159 (Arg127Ala, Arg130Ala) ) of human TSLP (Accession #NP_149024.1) fused with a 6×His tag at the C-t |
| Immunogen Region: | Tyr29-Gln159 |
| Immunogen Sequence: | YDFTNCDFEKIKAAYLSTIS KDLITYMSGTKSTEFNNTVS CSNRPHCLTEIQSLTFNPTA GCASLAKEMFAMKTKAALAI WCPGYSETQINATQAMKKAR KAKVTTNKCLEQVSQLQGLW RRFNRPLLKQQ |
| Function | Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin. |
| Protein Name | Thymic Stromal Lymphopoietin |
| Database Links | Reactome: R-HSA-1266695 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Thymic Stromal Lymphopoietin proteinTSLP protein |
Information sourced from Uniprot.org
