Human TRPV3 protein (Recombinant) (N-His) (STJP005722)

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STJP005722
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Short Description :Recombinant-Human TRPV3-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:TRPV3
Gene ID:162514
Uniprot ID:TRPV3_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Asn671-Val790
Function Non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. The channel pore can dilate to provide permeability to larger cations. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen).
Protein Name Transient Receptor Potential Cation Channel Subfamily V Member 3
Trpv3
Vanilloid Receptor-Like 3
Vrl-3
Database Links Reactome: R-HSA-3295583
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cytoplasm
Lysosome
Targeted To Lysosome For Degradation In A Snx11-Dependent Manner
Alternative Protein Names Transient Receptor Potential Cation Channel Subfamily V Member 3 protein
Trpv3 protein
Vanilloid Receptor-Like 3 protein
Vrl-3 protein
TRPV3 protein

Information sourced from Uniprot.org

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