Function | Is a membrane tether required for vesicle tethering to Golgi. Has an essential role in the maintenance of Golgi structure and function. It is required for efficient anterograde and retrograde trafficking in the early secretory pathway, functioning at both the ER-to-Golgi intermediate compartment (ERGIC) and Golgi complex. Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB-modulated transcription. |
Protein Name | Thyroid Receptor-Interacting Protein 11Tr-Interacting Protein 11Trip-11Clonal Evolution-Related Gene On Chromosome 14 ProteinGolgi-Associated Microtubule-Binding Protein 210Gmap-210Trip230 |
Database Links | Reactome: R-HSA-5620924Reactome: R-HSA-6811438Reactome: R-HSA-9703465 |
Cellular Localisation | Golgi ApparatusCis-Golgi Network MembranePeripheral Membrane ProteinCytoplasmCytoskeletonEndoplasmic Reticulum-Golgi Intermediate Compartment MembraneAssociates With The Ends Of Centrosome-Nucleated Microtubules |
Alternative Protein Names | Thyroid Receptor-Interacting Protein 11 proteinTr-Interacting Protein 11 proteinTrip-11 proteinClonal Evolution-Related Gene On Chromosome 14 Protein proteinGolgi-Associated Microtubule-Binding Protein 210 proteinGmap-210 proteinTrip230 proteinTRIP11 proteinCEV14 protein |
Information sourced from Uniprot.org