Human TRIAP1 protein (Recombinant) (His-Tag) (STJP018531)

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STJP018531
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Short Description :Recombinant-Human TRIAP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:TRIAP1
Gene ID:51499
Uniprot ID:TRIA1_HUMAN
Accession Number:NP_057483
Immunogen:Human
Immunogen Region:1-76aa
Immunogen Sequence:MNSVGEA CTDMKREYDQ CFNRWFAEKF LKGDSSGDPC TDLFKRYQQC VQKAIKEKEI PIEGLEFMGH GKEKPENSS
Function Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis.
Protein Name Tp53-Regulated Inhibitor Of Apoptosis 1
Protein 15e1.1
Wf-1
P53-Inducible Cell-Survival Factor
P53csv
Database Links Reactome: R-HSA-6803204
Reactome: R-HSA-9837999
Cellular Localisation Mitochondrion
Mitochondrion Intermembrane Space
Alternative Protein Names Tp53-Regulated Inhibitor Of Apoptosis 1 protein
Protein 15e1.1 protein
Wf-1 protein
P53-Inducible Cell-Survival Factor protein
P53csv protein
TRIAP1 protein
15E1.1 protein
HSPC132 protein

Information sourced from Uniprot.org

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