Tissue Specificity | Hypothalamus. Expressed in the hair follicle epithelium (at protein level). |
Post Translational Modifications | |
Function | As a component of the hypothalamic-pituitary-thyroid axis, it controls the secretion of thyroid-stimulating hormone (TSH) and is involved in thyroid hormone synthesis regulation. It also operates as modulator of hair growth. It promotes hair-shaft elongation, prolongs the hair cycle growth phase (anagen) and antagonizes its termination (catagen) by TGFB2. It stimulates proliferation and inhibits apoptosis of hair matrix keratinocytes. |
Protein Name | Pro-Thyrotropin-Releasing HormonePro-TrhProthyroliberin Cleaved Into - Thyrotropin-Releasing HormoneTrhProtirelinTsh-Releasing FactorThyroliberinThyrotropin-Releasing FactorTrf |
Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Pro-Thyrotropin-Releasing Hormone ELISA kitPro-Trh ELISA kitProthyroliberin Cleaved Into - Thyrotropin-Releasing Hormone ELISA kitTrh ELISA kitProtirelin ELISA kitTsh-Releasing Factor ELISA kitThyroliberin ELISA kitThyrotropin-Releasing Factor ELISA kitTrf ELISA kitTRH ELISA kit |
output | |
Information sourced from Uniprot.org