Human TRDMT1 protein (Recombinant) (His-Tag) (STJP017612)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017612
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General Information

Short DescriptionRecombinant-Human TRDMT1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 1mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolTRDMT1
Gene ID1787
Uniprot IDTRDMT_HUMAN
Accession NumberAAH47733
ImmunogenHuman
Immunogen Region1-391aa
Immunogen SequenceMEPLRV LELYSGVGGM HHALRESCIP AQVVAAIDVN TVANEVYKYN FPHTQLLAKT IEGITLEEFD RLSFDMILMS PPCQPFTRIG RQGDMTDSRT NSFLYILDIL PRLQKLPKYI LLENVKGFEV SSTRDLLIQT IENCGFQYQE FLLSPTSLGI PNSRLRYFLI AKLQSEPLPF QAPGQVLMEF PKIESVHPQK YAMDVE

Additional Info

Tissue Specificity Ubiquitous. Higher expression in testis, ovary and thymus and at much lower levels in spleen, prostate, colon, small intestine, and peripheral blood leukocytes.
Function Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp). Has higher activity on tRNA(Asp) modified with queuosine at position 34.
Protein Name Trna
Cytosine(38-C(5-Methyltransferase
Dna
Cytosine-5-Methyltransferase-Like Protein 2
Dnmt2
Dna Methyltransferase Homolog Hsaiip
Dna Mtase Homolog Hsaiip
M.hsaiip
Pumet
Database Links Reactome: R-HSA-6782315
Cellular Localisation Cytoplasm
Alternative Protein Names Trna protein
Cytosine(38-C(5-Methyltransferase protein
Dna protein
Cytosine-5-Methyltransferase-Like Protein 2 protein
Dnmt2 protein
Dna Methyltransferase Homolog Hsaiip protein
Dna Mtase Homolog Hsaiip protein
M.hsaiip protein
Pumet protein
TRDMT1 protein
DNMT2 protein

Information sourced from Uniprot.org

Citations

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