Human TRAILR3/TNFRSF10C protein (Recombinant) (His-Tag) (STJP019140)

Name: Human TRAILR3/TNFRSF10C protein (Recombinant) (His-Tag) (STJP019140)
SKU: STJP019140
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP019140

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Short Description	Recombinant-Human TRAILR3/TNFRSF10C-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	TNFRSF10C
Gene ID	8794
Uniprot ID	TR10C_HUMAN
Accession Number	NP_003832
Immunogen	Human
Immunogen Region	26-236aa
Immunogen Sequence	ATTARQE EVPQQTVAPQ QQRHSFKGEE CPAGSHRSEH TGACNPCTEG VDYTNASNNE PSCFPCTVCK SDQKHKSSCT MTRDTVCQCK EGTFRNENSP EMCRKCSRCP SGEVQVSNCT SWDDIQCVEE FGANATVETP AAEETMNTSP GTPAPAAEET MNTSPGTPAP AAEETMTTSP GTPAPAAEET MTTSPGTPAP AAEETM

Tissue Specificity	Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.
Post Translational Modifications	N-glycosylated and O-glycosylated.
Function	Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Protein Name	Tumor Necrosis Factor Receptor Superfamily Member 10c Antagonist Decoy Receptor For Trail/Apo-2l Decoy Trail Receptor Without Death Domain Decoy Receptor 1 Dcr1 Lymphocyte Inhibitor Of Trail Tnf-Related Apoptosis-Inducing Ligand Receptor 3 Trail Receptor 3 Trail-R3 Trail Receptor Without An Intracellular Domain Cd Antigen Cd263
Database Links	Reactome: R-HSA-6803211
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor
Alternative Protein Names	Tumor Necrosis Factor Receptor Superfamily Member 10c protein Antagonist Decoy Receptor For Trail/Apo-2l protein Decoy Trail Receptor Without Death Domain protein Decoy Receptor 1 protein Dcr1 protein Lymphocyte Inhibitor Of Trail protein Tnf-Related Apoptosis-Inducing Ligand Receptor 3 protein Trail Receptor 3 protein Trail-R3 protein Trail Receptor Without An Intracellular Domain protein Cd Antigen Cd263 protein TNFRSF10C protein DCR1 protein LIT protein TRAILR3 protein TRID protein UNQ321 protein PRO366 protein

Information sourced from Uniprot.org