Human TRAIL (Tumor Necrosis Factor Ligand Superfamily Member 10) Antibody Pair (STJAP00254)
General Information
| Short Description | This TRAIL antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Goat |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | TNFSF10 |
| Gene ID | 8743 |
| Uniprot ID | TNF10_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human TRAIL protein.Detection Immunogen: Recombinant Human TRAIL protein. |
Additional Info
| Post Translational Modifications | Tyrosine phosphorylated by PKDCC/VLK. |
| Function | Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 10Apo-2 LigandApo-2lTnf-Related Apoptosis-Inducing LigandProtein TrailCd Antigen Cd253 |
| Database Links | Reactome: R-HSA-140534Reactome: R-HSA-3371378Reactome: R-HSA-5213460Reactome: R-HSA-5218900Reactome: R-HSA-69416Reactome: R-HSA-75158 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinSecretedExists Both As Membrane-Bound And Soluble Form |
| Alternative Antibody Pair Names | Tumor Necrosis Factor Ligand Superfamily Member 10 antibody pairApo-2 Ligand antibody pairApo-2l antibody pairTnf-Related Apoptosis-Inducing Ligand antibody pairProtein Trail antibody pairCd Antigen Cd253 antibody pairTNFSF10 antibody pairAPO2L antibody pairTRAIL antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human TRAIL (Tumor Necrosis Factor Ligand Superfamily Member 10) Antibody Pair (STJAP00254)
This antibody pair detects human TRAIL (Tumor Necrosis Factor Ligand Superfamily Member 10, UniProt P50591) and has confirmed reactivity with human samples only.
The capture antibody is unconjugated and the detection antibody is biotinylated. Both are polyclonal goat antibodies supplied at 0.5 mg/mL in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.4.
This antibody pair has been validated for use in ELISA only. No other assay formats are listed in the product documentation.
Both antibodies were purified by antigen affinity purification and were each raised against recombinant human TRAIL protein as the immunogen.
Both components should be stored at -20 degrees Celsius for long-term storage. Freeze-thaw cycles should be avoided to maintain product integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.