Human TPSAB1/Tryptase-1 protein (Recombinant) (C-His) (STJP007255)

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STJP007255
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TPSAB1/Tryptase-1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TPSAB1
Gene ID: 7177
Uniprot ID: TRYB1_HUMAN
Immunogen Region: Met1-Pro275
Immunogen: Homo sapiens (Human)
Function Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.
Protein Name Tryptase Alpha/Beta-1
Tryptase-1
Tryptase I
Tryptase Alpha-1
Database Links Reactome: R-HSA-1592389
Cellular Localisation Secreted
Released From The Secretory Granules Upon Mast Cell Activation
Alternative Protein Names Tryptase Alpha/Beta-1 protein
Tryptase-1 protein
Tryptase I protein
Tryptase Alpha-1 protein
TPSAB1 protein
TPS1 protein
TPS2 protein
TPSB1 protein

Information sourced from Uniprot.org

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