Human TPP1 protein (Recombinant) (C-His) (STJP010153)

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STJP010153
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TPP1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TPP1
Gene ID: 1200
Uniprot ID: TPP1_HUMAN
Immunogen Region: Met1-Pro563
Immunogen: Homo sapiens (Human)
Post Translational Modifications Activated by autocatalytic proteolytical processing upon acidification. N-glycosylation is required for processing and activity.
Function Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus.
Protein Name Tripeptidyl-Peptidase 1
Tpp-1
Cell Growth-Inhibiting Gene 1 Protein
Lysosomal Pepstatin-Insensitive Protease
Lpic
Tripeptidyl Aminopeptidase
Tripeptidyl-Peptidase I
Tpp-I
Database Links Reactome: R-HSA-381038
Cellular Localisation Lysosome
Melanosome
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Protein Names Tripeptidyl-Peptidase 1 protein
Tpp-1 protein
Cell Growth-Inhibiting Gene 1 Protein protein
Lysosomal Pepstatin-Insensitive Protease protein
Lpic protein
Tripeptidyl Aminopeptidase protein
Tripeptidyl-Peptidase I protein
Tpp-I protein
TPP1 protein
CLN2 protein
GIG1 protein
UNQ267 protein
PRO304 protein

Information sourced from Uniprot.org

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