Function | Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore. Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases. |
Protein Name | Mitochondrial Import Receptor Subunit Tom22 HomologHtom221c9-2Translocase Of Outer Membrane 22 Kda Subunit Homolog |
Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-5205685 |
Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane Protein |
Alternative Protein Names | Mitochondrial Import Receptor Subunit Tom22 Homolog proteinHtom22 protein1c9-2 proteinTranslocase Of Outer Membrane 22 Kda Subunit Homolog proteinTOMM22 proteinTOM22 protein |
Information sourced from Uniprot.org