Human TNFRSF9/4-1BB/CD137 protein (Recombinant) (C-6His) (STJP002895)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Leukemia inhibitory factor/LIF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu24-Gln186) of human TNFRSF9/4-1BB/CD137 (Accession #NP_002300.1) fused with a 6×His tag at the C
General Information
| Short Description | Recombinant-Human TNFRSF9/4-1BB/CD137-C-6His protein was developed in hek293 cells using the region Leu24-Gln186. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured by its binding ability in a functional ELISA.Immobilized Human TNFRSF9 at 2 Mu g/mL (100 Mu L/well) can bind Human TNFSF9 with a linear range of 1-4.4 ng/mL. |
| Determination Method | < 0.1 EU/Mu g |
Target Information
| Gene Symbol | TNFRSF9 |
| Gene ID | 3604 |
| Uniprot ID | TNR9_HUMAN |
| Immunogen | Recombinant Human Leukemia inhibitory factor/LIF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu24-Gln186) of human TNFRSF9/4-1BB/CD137 (Accession #NP_002300.1) fused with a 6×His tag at the C |
| Immunogen Region | Leu24-Gln186 |
| Immunogen Sequence | LQDPCSNCPAGTFCDNNRNQ ICSPCPPNSFSSAGGQRTCD ICRQCKGVFRTRKECSSTSN AECDCTPGFHCLGAGCSMCE QDCKQGQELTKKGCKDCCFG TFNDQKRGICRPWTNCSLDG KSVLVNGTKERDVVCGPSPA DLSPGASSVTPPAPAREPGH SPQ |
Additional Info
| Function | Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable). |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 94-1bb Ligand ReceptorCdw137T-Cell Antigen 4-1bb HomologT-Cell Antigen IlaCd Antigen Cd137 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 9 protein4-1bb Ligand Receptor proteinCdw137 proteinT-Cell Antigen 4-1bb Homolog proteinT-Cell Antigen Ila proteinCd Antigen Cd137 proteinTNFRSF9 proteinCD137 proteinILA protein |
Information sourced from Uniprot.org