Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human TNFRSF7/CD27-C-hFc & His protein was developed from hek293 cells and has a target region of C-hFc & His. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Immunoreactivity: |
Measured by its binding ability in a functional ELISA. Immobilized Human CD27 at 2 Mu g/mL (100 Mu L/well) can bind Human CD70 with a linear range of 0.781-0.885 ng/mL. |
Gene Symbol: |
CD27 |
Gene ID: |
939 |
Uniprot ID: |
CD27_HUMAN |
Immunogen Region: |
Thr21-Ile192 |
Immunogen: |
Recombinant Human TNFRSF7/CD27 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Thr21-Ile192) of human CD27/TNFRSF7 (Accession #NP_001233.1) fused with a Fc, 6×His tag at the C-terminus. |
Post Translational Modifications | Phosphorylated. O-glycosylated with core 1 or possibly core 8 glycans. |
Function | Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. |
Protein Name | Cd27 AntigenCd27l ReceptorT-Cell Activation Antigen Cd27T14Tumor Necrosis Factor Receptor Superfamily Member 7Cd Antigen Cd27 |
Database Links | Reactome: R-HSA-5669034 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Cd27 Antigen proteinCd27l Receptor proteinT-Cell Activation Antigen Cd27 proteinT14 proteinTumor Necrosis Factor Receptor Superfamily Member 7 proteinCd Antigen Cd27 proteinCD27 proteinTNFRSF7 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance