| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | TNFRSF4 |
| Gene ID: | 7293 |
| Uniprot ID: | TNR4_HUMAN |
| Immunogen: | Recombinant Human TNFRSF4/OX40/CD134 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu29-Ala216) of Human OX40/TNFRSF4/CD134 (Accession #P43489) fused with a C-hFc tag at the C-terminus. |
| Immunogen Region: | Leu29-Ala216 |
| Immunogen Sequence: | LHCVGDTYPSNDRCCHECRP GNGMVSRCSRSQNTVCRPCG PGFYNDVVSSKPCKPCTWCN LRSGSERKQLCTATQDTVCR CRAGTQPLDSYKPGVDCAPC PPGHFSPGDNQACKPWTNCT LAGKHTLQPASNSSDAICED RDPPATQPQETQGPPARPIT VQPTEAWPRTSQGPSTRPVE VPGGRAVA |
| Function | Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. (Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 4Act35 AntigenOx40l ReceptorTax Transcriptionally-Activated Glycoprotein 1 ReceptorCd Antigen Cd134 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 4 proteinAct35 Antigen proteinOx40l Receptor proteinTax Transcriptionally-Activated Glycoprotein 1 Receptor proteinCd Antigen Cd134 proteinTNFRSF4 proteinTXGP1L protein |
Information sourced from Uniprot.org
