Human TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily Member 1a) Antibody Pair (STJAP00200)
General Information
| Short Description | This TNFRSF1A antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Mouse/Goat |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Protein A or G.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | TNFRSF1A |
| Gene ID | 7132 |
| Uniprot ID | TNR1A_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human TNFRSF1A protein.Detection Immunogen: Recombinant Human TNFRSF1A protein. |
Additional Info
| Function | Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 1aTumor Necrosis Factor Receptor 1Tnf-R1Tumor Necrosis Factor Receptor Type ITnf-RiTnfr-IP55P60Cd Antigen Cd120a Cleaved Into - Tumor Necrosis Factor Receptor Superfamily Member 1a - Membrane Form - Tumor Necrosis Factor-Binding Protein 1Tbpi |
| Database Links | Reactome: R-HSA-5357786Reactome: R-HSA-5357905Reactome: R-HSA-5357956Reactome: R-HSA-5626978Reactome: R-HSA-5669034Reactome: R-HSA-6783783Reactome: R-HSA-75893 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinGolgi Apparatus MembraneSecretedA Secreted Form Is Produced Through Proteolytic ProcessingIsoform 4: SecretedLacks A Golgi-Retention MotifIs Not Membrane Bound And Therefore Is Secreted |
| Alternative Antibody Pair Names | Tumor Necrosis Factor Receptor Superfamily Member 1a antibody pairTumor Necrosis Factor Receptor 1 antibody pairTnf-R1 antibody pairTumor Necrosis Factor Receptor Type I antibody pairTnf-Ri antibody pairTnfr-I antibody pairP55 antibody pairP60 antibody pairCd Antigen Cd120a Cleaved Into - Tumor Necrosis Factor Receptor Superfamily Member 1a - Membrane Form - Tumor Necrosis Factor-Binding Protein 1 antibody pairTbpi antibody pairTNFRSF1A antibody pairTNFAR antibody pairTNFR1 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily Member 1a) Antibody Pair (STJAP00200)
This antibody pair detects human TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily Member 1a), corresponding to UniProt accession P19438. Reactivity is confirmed for human samples only.
The capture antibody is an unconjugated mouse monoclonal antibody and the detection antibody is a biotin-conjugated goat polyclonal antibody. Both components are supplied at 0.5 mg/mL, formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.4.
This pair is validated for use in ELISA. No other assay formats are listed in the product specifications.
Both the capture and detection antibodies were raised against recombinant human TNFRSF1A protein. The capture antibody was purified by Protein A or G, while the detection antibody was purified by antigen affinity.
Both components should be stored at -20°C for long-term storage. Freeze-thaw cycles should be avoided to maintain reagent integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.