Human TMOD1 protein (Recombinant) (N-His) (STJP004468)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP004468
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General Information

Short DescriptionRecombinant-Human TMOD1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolTMOD1
Gene ID7111
Uniprot IDTMOD1_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionPro39-His138

Additional Info

Function Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
Protein Name Tropomodulin-1
Erythrocyte Tropomodulin
E-Tmod
Database Links Reactome: R-HSA-390522
Cellular Localisation Cytoplasm
Cytoskeleton
In Myofibrils With Sarcomeric Structure
Localizes To The Pointed End Of Actin Thin Filaments
Alternative Protein Names Tropomodulin-1 protein
Erythrocyte Tropomodulin protein
E-Tmod protein
TMOD1 protein
D9S57E protein
TMOD protein

Information sourced from Uniprot.org

Citations

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