Human TLE5 protein (Recombinant) (N-His-KSI) (STJP015874)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human TLE5-N-His-KSI protein was developed from e.coli for the region N-His-KSI. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | TLE5 |
| Gene ID | 166 |
| Uniprot ID | TLE5_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met2-Asp197 |
Additional Info
| Post Translational Modifications | Ubiquitinated by XIAP/BIRC4. |
| Function | Transcriptional corepressor. Acts as a dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development. |
| Protein Name | Tle Family Member 5Amino-Terminal Enhancer Of SplitAmino Enhancer Of SplitGp130-Associated Protein GamGrg-5Groucho-Related Protein 5Protein Esp1Protein GrgTle Family Member 5 - Transcriptional Modulator |
| Database Links | Reactome: R-HSA-4641265 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Tle Family Member 5 proteinAmino-Terminal Enhancer Of Split proteinAmino Enhancer Of Split proteinGp130-Associated Protein Gam proteinGrg-5 proteinGroucho-Related Protein 5 proteinProtein Esp1 proteinProtein Grg proteinTle Family Member 5 - Transcriptional Modulator proteinTLE5 proteinAES proteinGRG proteinGRG5 protein |
Information sourced from Uniprot.org