| Function | Plays a role in tight junctions and adherens junctions. Acts as a positive regulator of RANKL-induced osteoclast differentiation, potentially via mediating downstream transcriptional activity. |
| Protein Name | Tight Junction Protein 2Tight Junction Protein Zo-2Zona Occludens Protein 2Zonula Occludens Protein 2 |
| Database Links | Reactome: R-HSA-2028269Reactome: R-HSA-351906Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106 |
| Cellular Localisation | Cell JunctionAdherens JunctionCell MembranePeripheral Membrane ProteinCytoplasmic SideTight JunctionNucleusAlso Nuclear Under Environmental Stress Conditions And In Migratory Endothelial Cells And Subconfluent Epithelial Cell CulturesLocalizes To Tight Junctions During Initial Stages Of Their Formation |
| Alternative Protein Names | Tight Junction Protein 2 proteinTight Junction Protein Zo-2 proteinZona Occludens Protein 2 proteinZonula Occludens Protein 2 proteinTJP2 proteinX104 proteinZO2 protein |
Information sourced from Uniprot.org