Human TJP2 protein (Recombinant) (N-His) (STJP006145)

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STJP006145
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TJP2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TJP2
Gene ID: 9414
Uniprot ID: ZO2_HUMAN
Immunogen Region: Gly307-Ala669
Immunogen: Homo sapiens (Human)
Function Plays a role in tight junctions and adherens junctions. Acts as a positive regulator of RANKL-induced osteoclast differentiation, potentially via mediating downstream transcriptional activity.
Protein Name Tight Junction Protein Zo-2
Tight Junction Protein 2
Zona Occludens Protein 2
Zonula Occludens Protein 2
Database Links Reactome: R-HSA-2028269
Reactome: R-HSA-351906
Reactome: R-HSA-8980692
Reactome: R-HSA-9013026
Reactome: R-HSA-9013106
Cellular Localisation Cell Junction
Adherens Junction
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Tight Junction
Nucleus
Also Nuclear Under Environmental Stress Conditions And In Migratory Endothelial Cells And Subconfluent Epithelial Cell Cultures
Alternative Protein Names Tight Junction Protein Zo-2 protein
Tight Junction Protein 2 protein
Zona Occludens Protein 2 protein
Zonula Occludens Protein 2 protein
TJP2 protein
X104 protein
ZO2 protein

Information sourced from Uniprot.org