Host: |
E. coli |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : |
Recombinant-Human TJP2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: |
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: |
TJP2 |
Gene ID: |
9414 |
Uniprot ID: |
ZO2_HUMAN |
Immunogen Region: |
Gly307-Ala669 |
Immunogen: |
Homo sapiens (Human) |
Function | Plays a role in tight junctions and adherens junctions. Acts as a positive regulator of RANKL-induced osteoclast differentiation, potentially via mediating downstream transcriptional activity. |
Protein Name | Tight Junction Protein Zo-2Tight Junction Protein 2Zona Occludens Protein 2Zonula Occludens Protein 2 |
Database Links | Reactome: R-HSA-2028269Reactome: R-HSA-351906Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106 |
Cellular Localisation | Cell JunctionAdherens JunctionCell MembranePeripheral Membrane ProteinCytoplasmic SideTight JunctionNucleusAlso Nuclear Under Environmental Stress Conditions And In Migratory Endothelial Cells And Subconfluent Epithelial Cell Cultures |
Alternative Protein Names | Tight Junction Protein Zo-2 proteinTight Junction Protein 2 proteinZona Occludens Protein 2 proteinZonula Occludens Protein 2 proteinTJP2 proteinX104 proteinZO2 protein |
Information sourced from Uniprot.org