Human TGIF2 protein (Recombinant) (N-His-SUMO) (STJP007948)

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STJP007948
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TGIF2-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TGIF2
Gene ID: 60436
Uniprot ID: TGIF2_HUMAN
Immunogen Region: Lys27-Thr92
Immunogen: Homo sapiens (Human)
Post Translational Modifications The C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway.
Function Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins.
Protein Name Homeobox Protein Tgif2
5'-Tg-3'-Interacting Factor 2
Tgf-Beta-Induced Transcription Factor 2
Tgfb-Induced Factor 2
Database Links Reactome: R-HSA-2173795
Reactome: R-HSA-2173796
Cellular Localisation Nucleus
Excluded From Nucleoli
Alternative Protein Names Homeobox Protein Tgif2 protein
5'-Tg-3'-Interacting Factor 2 protein
Tgf-Beta-Induced Transcription Factor 2 protein
Tgfb-Induced Factor 2 protein
TGIF2 protein

Information sourced from Uniprot.org

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